diff --git a/meta-python/conf/include/ptest-packagelists-meta-python.inc b/meta-python/conf/include/ptest-packagelists-meta-python.inc
index 4cbdec70a3..2a7be4f331 100644
--- a/meta-python/conf/include/ptest-packagelists-meta-python.inc
+++ b/meta-python/conf/include/ptest-packagelists-meta-python.inc
@@ -39,6 +39,7 @@ PTESTS_FAST_META_PYTHON = "\
     python3-gpt-image \
     python3-gunicorn \
     python3-h2 \
+    python3-hpack \
     python3-html2text \
     python3-httptools \
     python3-inflection \
diff --git a/meta-python/recipes-connectivity/python-hpack/python3-hpack_4.1.0.bb b/meta-python/recipes-connectivity/python-hpack/python3-hpack_4.1.0.bb
index a5b9130d00..4ecbd583f3 100644
--- a/meta-python/recipes-connectivity/python-hpack/python3-hpack_4.1.0.bb
+++ b/meta-python/recipes-connectivity/python-hpack/python3-hpack_4.1.0.bb
@@ -6,6 +6,14 @@ LIC_FILES_CHKSUM = "file://LICENSE;md5=5bf1c68e73fbaec2b1687b7e71514393"
 
 SRC_URI[sha256sum] = "ec5eca154f7056aa06f196a557655c5b009b382873ac8d1e66e79e87535f1dca"
 
-inherit pypi python_setuptools_build_meta
+inherit ptest-python-pytest pypi python_setuptools_build_meta
 
 RDEPENDS:${PN} += "python3-logging"
+RDEPENDS:${PN}-ptest += "python3-hypothesis"
+
+do_install_ptest:append(){
+    # One test is failing due to missing fixtures, upstream's recommended
+    # solution is to delete this file (as of v4.1.0):
+    # https://github.com/python-hyper/hpack/issues/272
+    rm -f ${D}${PTEST_PATH}/${PTEST_PYTEST_DIR}/conftest.py
+}