diff --git a/meta/classes-recipe/autotools.bbclass b/meta/classes-recipe/autotools.bbclass
index 9359c9b4e1..7ee1b0d9c7 100644
--- a/meta/classes-recipe/autotools.bbclass
+++ b/meta/classes-recipe/autotools.bbclass
@@ -254,8 +254,6 @@ autotools_do_install() {
 	fi
 }
 
-inherit siteconfig
-
 EXPORT_FUNCTIONS do_configure do_compile do_install
 
 B = "${WORKDIR}/build"
diff --git a/meta/classes-recipe/siteinfo.bbclass b/meta/classes-recipe/siteinfo.bbclass
index 68aefb8eda..25b53d929a 100644
--- a/meta/classes-recipe/siteinfo.bbclass
+++ b/meta/classes-recipe/siteinfo.bbclass
@@ -221,20 +221,6 @@ def siteinfo_get_files(d, sysrootcache=False):
         # This would show up as breaking sstatetests.SStateTests.test_sstate_32_64_same_hash for example
         searched = []
 
-    if not sysrootcache:
-        return sitefiles, searched
-
-    # Now check for siteconfig cache files in sysroots
-    path_siteconfig = d.getVar('SITECONFIG_SYSROOTCACHE')
-    if path_siteconfig and os.path.isdir(path_siteconfig):
-        for i in os.listdir(path_siteconfig):
-            if not i.endswith("_config"):
-                continue
-            filename = os.path.join(path_siteconfig, i)
-            sitefiles.append(filename)
     return sitefiles, searched
 
-#
-# Make some information available via variables
-#
-SITECONFIG_SYSROOTCACHE = "${STAGING_DATADIR}/${TARGET_SYS}_config_site.d"
+
diff --git a/meta/classes-recipe/toolchain-scripts.bbclass b/meta/classes-recipe/toolchain-scripts.bbclass
index cbef412e79..b59a295abc 100644
--- a/meta/classes-recipe/toolchain-scripts.bbclass
+++ b/meta/classes-recipe/toolchain-scripts.bbclass
@@ -201,7 +201,6 @@ EOF
 
 #we get the cached site config in the runtime
 TOOLCHAIN_CONFIGSITE_NOCACHE = "${@' '.join(siteinfo_get_files(d)[0])}"
-TOOLCHAIN_CONFIGSITE_SYSROOTCACHE = "${STAGING_DIR}/${MLPREFIX}${MACHINE}/${target_datadir}/${TARGET_SYS}_config_site.d"
 TOOLCHAIN_NEED_CONFIGSITE_CACHE ??= "virtual/${MLPREFIX}libc ncurses"
 DEPENDS += "${TOOLCHAIN_NEED_CONFIGSITE_CACHE}"
 
@@ -223,14 +222,8 @@ toolchain_create_sdk_siteconfig () {
 			sitefile=`echo $sitefile | tr / _`
 			sitefile=`cat ${STAGING_DIR_TARGET}/sysroot-providers/$sitefile`
 		esac
-
-		if [ -r ${TOOLCHAIN_CONFIGSITE_SYSROOTCACHE}/${sitefile}_config ]; then
-			cat ${TOOLCHAIN_CONFIGSITE_SYSROOTCACHE}/${sitefile}_config >> $siteconfig
-		fi
 	done
 }
-# The immediate expansion above can result in unwanted path dependencies here
-toolchain_create_sdk_siteconfig[vardepsexclude] = "TOOLCHAIN_CONFIGSITE_SYSROOTCACHE"
 
 python __anonymous () {
     import oe.classextend
diff --git a/meta/classes/siteconfig.bbclass b/meta/classes/siteconfig.bbclass
deleted file mode 100644
index 953cafd285..0000000000
--- a/meta/classes/siteconfig.bbclass
+++ /dev/null
@@ -1,39 +0,0 @@
-#
-# Copyright OpenEmbedded Contributors
-#
-# SPDX-License-Identifier: MIT
-#
-
-python siteconfig_do_siteconfig () {
-    shared_state = sstate_state_fromvars(d)
-    if shared_state['task'] != 'populate_sysroot':
-        return
-    if not os.path.isdir(os.path.join(d.getVar('FILE_DIRNAME'), 'site_config')):
-        bb.debug(1, "No site_config directory, skipping do_siteconfig")
-        return
-    sstate_install(shared_state, d)
-    bb.build.exec_func('do_siteconfig_gencache', d)
-    sstate_clean(shared_state, d)
-}
-
-EXTRASITECONFIG ?= ""
-
-siteconfig_do_siteconfig_gencache () {
-	mkdir -p ${WORKDIR}/site_config_${MACHINE}
-	gen-site-config ${FILE_DIRNAME}/site_config \
-		>${WORKDIR}/site_config_${MACHINE}/configure.ac
-	cd ${WORKDIR}/site_config_${MACHINE}
-	autoconf
-	rm -f ${BPN}_cache
-	CONFIG_SITE="" ${EXTRASITECONFIG} ./configure ${CONFIGUREOPTS} --cache-file ${BPN}_cache
-	sed -n -e "/ac_cv_c_bigendian/p" -e "/ac_cv_sizeof_/p" \
-		-e "/ac_cv_type_/p" -e "/ac_cv_header_/p" -e "/ac_cv_func_/p" \
-		< ${BPN}_cache > ${BPN}_config
-	mkdir -p ${SYSROOT_DESTDIR}${datadir}/${TARGET_SYS}_config_site.d
-	cp ${BPN}_config ${SYSROOT_DESTDIR}${datadir}/${TARGET_SYS}_config_site.d
-
-}
-
-do_populate_sysroot[sstate-interceptfuncs] += "do_siteconfig "
-
-EXPORT_FUNCTIONS do_siteconfig do_siteconfig_gencache
diff --git a/meta/recipes-core/ncurses/ncurses.inc b/meta/recipes-core/ncurses/ncurses.inc
index 2a3fd4f2c5..f5e37b94da 100644
--- a/meta/recipes-core/ncurses/ncurses.inc
+++ b/meta/recipes-core/ncurses/ncurses.inc
@@ -20,8 +20,6 @@ EXTRA_AUTORECONF = "-I m4"
 CACHED_CONFIGUREVARS = "cf_cv_func_nanosleep=yes"
 CACHED_CONFIGUREVARS:append:linux = " cf_cv_working_poll=yes"
 
-EXTRASITECONFIG = "CFLAGS='${CFLAGS} -I${SYSROOT_DESTDIR}${includedir}'"
-
 # Whether to enable separate widec libraries; must be 'true' or 'false'
 #
 # TODO: remove this variable when widec is supported in every setup?
diff --git a/meta/recipes-core/ncurses/site_config/headers b/meta/recipes-core/ncurses/site_config/headers
deleted file mode 100644
index 087b7bfd5e..0000000000
--- a/meta/recipes-core/ncurses/site_config/headers
+++ /dev/null
@@ -1,5 +0,0 @@
-curses.h
-ncurses/curses.h
-ncurses.h
-ncurses/termcap.h
-
diff --git a/meta/recipes-core/zlib/site_config/headers b/meta/recipes-core/zlib/site_config/headers
deleted file mode 100644
index 50268918aa..0000000000
--- a/meta/recipes-core/zlib/site_config/headers
+++ /dev/null
@@ -1 +0,0 @@
-zlib.h
diff --git a/scripts/gen-site-config b/scripts/gen-site-config
deleted file mode 100755
index 727b809c0f..0000000000
--- a/scripts/gen-site-config
+++ /dev/null
@@ -1,43 +0,0 @@
-#! /bin/sh
-#  Copyright (c) 2005-2008 Wind River Systems, Inc.
-#
-# SPDX-License-Identifier: GPL-2.0-only
-#
-
-cat << EOF
-AC_PREREQ(2.57)
-AC_INIT([site_wide],[1.0.0])
-
-EOF
-
-# Disable as endian is set in the default config
-#echo AC_C_BIGENDIAN
-#echo
-
-if [ -e $1/types ] ; then
-  while read type ; do
-    echo "AC_CHECK_SIZEOF([$type])"
-  done < $1/types
-
-  echo
-fi
-
-if [ -e $1/funcs ]; then
-  while read func ; do
-    echo "AC_CHECK_FUNCS([$func])"
-  done < $1/funcs
-
-  echo
-fi
-
-if [ -e $1/headers ]; then
-  while read header ; do
-    echo "AC_CHECK_HEADERS([$header])"
-  done < $1/headers
-
-  echo
-fi
-
-cat << EOF
-AC_OUTPUT
-EOF